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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R8
All Species:
27.27
Human Site:
S249
Identified Species:
50
UniProt:
Q12972
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12972
NP_002704.1
351
38479
S249
G
S
L
G
L
E
E
S
G
S
R
R
M
Q
N
Chimpanzee
Pan troglodytes
XP_001150604
378
41336
S249
G
S
L
G
L
E
E
S
G
S
R
R
M
Q
N
Rhesus Macaque
Macaca mulatta
XP_001112289
378
41328
S249
G
S
L
G
L
E
E
S
G
S
R
R
M
Q
N
Dog
Lupus familis
XP_865789
355
39236
S253
G
S
L
G
L
E
E
S
G
S
R
R
M
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3G1
351
38509
S249
G
S
L
G
L
E
E
S
G
S
R
R
M
Q
N
Rat
Rattus norvegicus
NP_001101381
351
38521
S249
G
S
L
G
L
E
E
S
G
S
R
R
M
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518825
234
26189
L133
L
R
E
K
P
Q
T
L
P
S
A
T
K
G
D
Chicken
Gallus gallus
NP_001026062
354
38600
S250
G
S
L
T
T
D
D
S
A
T
R
R
M
Q
N
Frog
Xenopus laevis
NP_001083528
346
37932
E244
I
T
G
S
L
S
L
E
D
S
V
G
R
R
V
Zebra Danio
Brachydanio rerio
NP_001094422
351
38384
N246
S
T
L
G
L
D
E
N
V
A
R
R
L
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611177
383
42555
N240
H
M
G
I
H
S
G
N
S
S
L
S
S
A
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492781
302
33933
L201
S
V
G
R
F
R
N
L
V
T
T
A
I
I
S
Sea Urchin
Strong. purpuratus
XP_001199058
347
38163
S244
S
G
L
V
G
D
P
S
V
K
T
M
Q
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.8
91.2
89
N.A.
98
97.7
N.A.
65.8
88.6
82.9
77.7
N.A.
47.5
N.A.
39
51.5
Protein Similarity:
100
91.8
91.5
90.4
N.A.
98.5
98.5
N.A.
66
93.2
89.7
88
N.A.
62.1
N.A.
53.8
67.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
60
13.3
53.3
N.A.
13.3
N.A.
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
80
26.6
86.6
N.A.
20
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
8
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
24
8
0
8
0
0
0
0
0
8
% D
% Glu:
0
0
8
0
0
47
54
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
54
8
24
54
8
0
8
0
47
0
0
8
0
16
0
% G
% His:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% K
% Leu:
8
0
70
0
62
0
8
16
0
0
8
0
8
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
54
0
0
% M
% Asn:
0
0
0
0
0
0
8
16
0
0
0
0
0
0
70
% N
% Pro:
0
0
0
0
8
0
8
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
8
62
0
% Q
% Arg:
0
8
0
8
0
8
0
0
0
0
62
62
8
8
0
% R
% Ser:
24
54
0
8
0
16
0
62
8
70
0
8
8
0
8
% S
% Thr:
0
16
0
8
8
0
8
0
0
16
16
8
0
0
0
% T
% Val:
0
8
0
8
0
0
0
0
24
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _